The cord blood: What You Should Know
The cord blood is present in the blood vessels of the placenta and umbilical cord, and is collected after the baby is born and then cut the umbilical cord; an important detail.
"Because cord blood is usually collected after delivery and after cutting the cord, intervention is generally safe for both mother and baby," says Dr. Keith Wonnacott, PhD, Branch Chief Therapies Office Phones Cell Therapies, Tissue and Genetic FDA.
The use of cord blood is only approved for interventions "hematopoietic stem cell transplantation," which was performed in patients with disorders of the hematopoietic (blood producing). The cord blood contains blood cell production can be used to treat patients with cancers of the blood such as leukemias and lymphomas, as well as certain blood disorders and immune system, such as stem cells of sickle cell anemia and Wiskott-Aldrich
"The cord blood is useful because it is a source of stem cells that are transformed into blood cells. Cord blood transplants can be used for people who need feedback, ie ´re-produce´ these cells producing blood cells, "says Dr. Wonnacott.
For example, in many cancer patients, the disease is found in the blood cells. Chemotherapy to treat these patients undergoing cancer cells eliminates both as producing healthy stem cells of blood cells. Transplantation of umbilical cord stem cells can support the regeneration of blood cells following chemotherapy.
However, the cord blood is not a cure-all.
"Given that cord blood contains stem cells, have been several cases of fraud related to cord blood," says Dr. Wonnacott. "Consumers think that stem cells can cure all diseases, but science has not shown this to be true.Patients should maintain skepticism if the cord blood is available for uses other than blood regeneration by stem "cells.
Information about the storage of cord blood
After obtaining the cord blood is frozen and can be stored safely for many years. "The method of freeze-called ´criopreservación´-is very important to maintain the integrity of the cells," says Dr. Wonnacott. "The cord blood will be stored with care."
Blood from the umbilical cord can be stored in a private bank, so it is available if the baby in the future-or relatives of first or second degree, they need it. The private cord banks typically charge for the collection and storage of blood.
Alternatively, blood can be donated to a public bank so that doctors can use to treat patients who need blood stem cell transplants.
The FDA regulates the cord blood in different ways, depending on its origin, processing level and intended use.
The stored cord blood for personal use, use in relatives of first or second degree, and that also meets other requirements of the FDA regulations, does not need the consent of this body before being used. Still, private cord banks must comply with other requirements of the FDA, including those that require them to register and enroll in the listings, be updated on the proper use of tissues standards, testing and analysis and detection of diseases infectious patients (except when the cord blood is going to be used by the original donor). These FDA requirements ensure the safety of these products to minimize the risk of contamination and transmission of infectious diseases.
The cord blood is stored to treat patients with unrelated donor is eligible to be considered a "drug" and a "biological product". The cord blood in this category must meet additional requirements and be authorized in accordance with a Biologics License Application, or be subjected to research new drug application before it can be used. The FDA requirements help ensure the safety and efficacy of the products in their intended uses.
Not all units of cord blood meeting the requirements necessary to be stored in a public bank, added Safa Karandish, MT, safety officer for the FDA Consumer. If this happens, part of the donated cord blood may be used for non-clinical research.
Tips for Consumers
If you are considering donating to bank cord blood, it is important to study the various options during pregnancy to have enough time to make a decision before the baby is born. If you want to donate to a public bank, ask if the hospital will give birth in a program storage of cord blood.
If you have questions about the risks and the procedures followed to obtain blood, or the donation process, ask your doctor.
The FDA also has a database which is available with information on banks registered cord blood.
All assertions that the cord blood is a miracle cure is not created; it is not. Some parents may consider using a private bank as an "insurance policy" against diseases that may arise in the future. But it is important to remember that currently the only approved use of cord blood is the treatment of hematologic (blood disorders).
Also good to know that, in some cases, the cord blood is stored may not be appropriate for the child who donated."For example, it is not possible to cure some diseases or genetic defects with cord blood containing the same disease or defect," says Karandish.
Parents of children from ethnic minorities should especially consider donating to a public bank, says Dr. Wonnacott, because the more donations make these groups receive more help minority patients who need a stem cell transplant. (Recipients must be "compatible" with donors so that doctors are more likely to find a good candidate among donors within the ethnic group of the receiver).
"As far as public banks is concerned, there is a clear need for cord blood," says Dr. Wonnacott. "And there is a need especially among minorities to have stem cell transplants. The cord blood is an excellent source of stem cells for transplantation. "
And these transplants can change the lives of patients.
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A problem in the city: A GREAT CONSUMPTION OF ALCOHOL IN ADOLESCENCE CAN IMPAIR THE BRAIN PERMANENTLY
To drink much during the teens years could lead to structural changes in the brain and memory deficits that persist in the adult phase, according to the disturbing results of a study done on animals. The study found that, even as adults, rats who had daily access to alcohol during his adolescence had reduced levels of myelin. With a function not very different from the insulation of electrical wiring, myelin forms an insulating layer that surrounds the axons. These are filiform extensions of neurons that transmit nerve impulses.
These brain changes in rats were observed in a region important for reasoning and decision-making. Animals who drank more alcohol performed worse on a test of memory made when they were adults. The results suggest that high doses of alcohol during adolescence may continue affecting the brain even when the inpidual has left the consumption of alcohol. More research is needed to determine if these findings can be applied to humans.
According to the World Health Organization, a growing number of teens and young adults is provided to drinking to get drunk, consuming four (five for men) or more drinks in about two hours. Previous research in humans have shown an association between an episode of drinking excessive (binge) in adolescence, changes in the myelin sheath in several brain regions, and cognitive impairments in adulthood. However, it was unknown if alcohol was behind these brain differences and behaviour or if there was predisposition factors that could explain the found.
In this study, Heather N. Richardson, Wanette M. Vargas, Lynn Bengston and Brian. W. Whitcomb, of the University of Massachusetts in Amherst American city, as well as Nicholas W. Gilpin, of the State University of Louisiana in New Orleans, United States, compared the myelin in the prefrontal cortex (an area of the brain that is vital to reason and make decisions) in young male rats who gave a daily sweetened alcohol or sweetened water access for two weeks. It was found that animals that drank alcohol in his teens experienced a reduction in the levels of myelin in the prefrontal cortex, compared with those who drank a similar amount of sweetened water. When the researchers examined the animals exposed to the alcohol several months later, they found that continued showing levels of myelin reduced as adults.
Exercise not only improves bone health, it also increases muscle strength, coordination and balance and helps improve overall health.
Bones, like muscles, are living tissue that responds to exercise by becoming stronger. In general, women and young men who exercise regularly reach a higher bone density (the highest level of consistency and strength of bones) than those who do not exercise. Most people reach peak bone density between 20 and 30 years old. From that age usually bone density begins to decrease. Women and men over age 20 can help prevent bone loss hacienda exercise frequently. The exercise allows us to maintain muscle strength, coordination and balance, which in turn helps prevent falls and fractures. This is especially important for older adults and people who have been diagnosed with osteoporosis.
The best exercise for your bones is required weight-bearing. This type of exercise makes you strive to work against gravity. Examples of these exercises include weight lifting, walking, hiking, jogging, stair climbing, tennis and dance. In contrast, exercises that do not require weight-bearing include swimming and cycling. While these exercises help strengthen and maintain strong muscles and reduce the risk of cardiovascular disease, are not the most effective in strengthening bones.
If you have health problems such as heart problems, high blood pressure, diabetes or obesity, or if you are 40 years old or more, consult your doctor before you start exercising regularly. According to the Surgeon General, the optimal goal is to exercise for at least 30 minutes most days; preferably daily.
Pay attention to your body. When starting an exercise routine, you may have some pain and discomfort in the muscles, but should not be painful or last more than 48 hours. If this occurs, you may be working too hard and need to slow down. Stop exercising if you feel any pain or discomfort in the chest and talk to your doctor before your next workout.
If you have osteoporosis, it is important to ask your doctor what activities are safe for you. If you have low bone density, experts recommend that the column is protected and avoiding exercises or activities that cause bending or twisting of the back. Moreover, should avoid high-impact exercise to reduce the risk of breaking a bone. You can also consult with an exercise specialist to teach you the proper progression of their activities, to stretch and strengthen muscles safely, and correct bad posture habits. An exercise specialist should have a degree in exercise physiology, physical education, physiotherapy or similar specialty. Be sure to ask if you are familiar with the special needs of people with osteoporosis.
Remember, exercise is only part of a regimen for the prevention or treatment of osteoporosis. Like a diet rich in calcium and vitamin D, exercise helps strengthen bones at any age. But it is possible that good nutrition and exercise are not enough to stop the loss of bone density caused by medical conditions, menopause or certain habits such as the use of snuff and excessive consumption of alcohol. It is important to talk to your doctor about your bone health. Ask if you are a candidate for a bone density test. If densitometry shows low bone mass, ask what medications may help maintain healthy bones and fight osteoporosis.